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Mebendazole interferes with glucose uptake in nematodes and cestodes. The uptake of http://www.asscat.org exogenous glucose in A. The inhibition of glucose transport in A. The blocking of glucose utilisation or its transport leads to decreased ATP synthesis causing depletion of the energy source in the worm. The cytoplasmic and mitochondrial MDH obtained from A. According to McCracken and Stilwell, the benzimidazole anthelmintics may act as lipid-soluble proton conductors both in artificial phospholipid bilayer and natural rat-liver mitochondria membrane systems. These drugs disturb the transmembrane proton gradient severely, leading to a considerable drop in cellular ATP levels. The in vitro and in vivo results obtained by these authors would indicate that the mode of action of benzimidazole may be, in part, due to a bioenergetic disruption caused by transmembrane proton discharge. Vardanyan, V. Hruby, in Synthesis of Essential Drugs,

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Mebendazole MBZ is a medication used to treat a number of parasitic worm infestations. Mebendazole is usually well tolerated. Mebendazole came into use in, after it was developed by Janssen Pharmaceutica in Belgium.

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Sigrid (taken for 2 to 4 years) 05.12.2019

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An employee of GlaxoSmithKline Pharmaceuticals holds bottles of albendazole, an anti-hookworm medication. The 4 cents is in Tanzania. The pill will put an end to the problems hookworm can cause, such as anemia and protein deficiency as well as stunting growth in children.

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Erwin (taken for 3 to 4 years) 23.10.2019

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A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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Benedikt (taken for 2 to 5 years) 18.05.2016

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The control of soil-transmitted helminth STH infections currently relies on the large-scale administration of single-dose oral albendazole or mebendazole. We compared the efficacy of single-dose versus triple-dose treatment against hookworm and other STHs in a community-based randomized controlled trial in the People's Republic of China.

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Martin (taken for 3 to 6 years) 07.12.2019

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