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It is recommended that treatment is started while the patient is still smoking and a target stop date set within the first two weeks of treatment with Zyban, preferably in the second week. The initial dose is mg to be taken daily for six days, increasing on day seven to mg twice daily. The maximum single dose must not exceed mg and the maximum total daily dose must not exceed mg. Insomnia is a very common adverse event which can be reduced by avoiding bedtime doses of Zyban provided there is at least 8 hours between doses. Use in patients under 18 years of age is not recommended as the safety and efficacy of Zyban tablets have not been evaluated in these patients. Zyban should be used with caution in older people. Greater sensitivity in some older individuals cannot be ruled out. The recommended dose in older people is mg once a day see section 4. Zyban should be used with caution in patients with hepatic impairment. Because of increased variability in the pharmacokinetics in patients with mild to moderate impairment the recommended dose in these patients is mg once a day.
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Common side effects of bupropion include a dry mouth, difficulty sleeping, agitation, and headaches. Bupropion is an atypical antidepressant. Bupropion was first made by chemist Nariman Mehta in, and patented by Burroughs Wellcome in Bupropion was approved by the U. Bupropion has several features that distinguish it from other antidepressants: for instance, unlike the majority of antidepressants, it does not usually cause sexual dysfunction. The addition to a prescribed SSRI is a common strategy when people do not respond to the SSRI, even though this is not an officially approved indication.
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The antidepressant drug Zyban is one of the newest — and reportedly one of the most effective — weapons in the anti-smoking arsenal. What is Zyban?
Therapeutic Class: Antidepressants: Zyban Bupropion.
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Zyban is a comparative smoking aids treatment, made by GlaxoSmithKline.
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