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Common side effects include sleepiness, headache, vomiting, trouble with coordination, and rash. Lamotrigine was first marketed in the United Kingdom in, and approved for use in the United States in Lamotrigine is considered a first-line drug for primary generalized tonic-clonic seizures includes simple partial, complex partial, and secondarily generalized seizures such as focal-onset tonic-clonic seizures. It is also used as an alternative or adjuvant medication for partial seizures, such as absence seizure, myoclonic seizure, and atonic seizures. Lamotrigine is approved in the US for maintenance treatment of bipolar I disorder and bipolar II disorder. The drug seems ineffective in the treatment of current rapid-cycling, acute mania, or acute depression in bipolar disorder; however, it is effective at prevention of or delaying of manic, depressive, or rapid cycling episodes. Therapeutic benefit is less evident when lamotrigine is used to treat a current-mood episode.
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Lamictal is a decent drug. Nothing has stopped my seizures but lamictal has fewer side effects than most.
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