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Federal regulators yesterday approved the nation's top-selling allergy drug, Claritin, as an over-the-counter medicine, a decision that will bring substantial savings for the uninsured and allow all patients to obtain the drug without a trip to the doctor. The decision will raise costs for many allergy patients with insurance, however, because insurers will no longer cover most of the cost of Claritin. Wellpoint, the large California insurer that prompted the Food and Drug Administration's evaluation of Claritin, has also asked the agency to make Clarinex, Schering-Plough's newest allergy drug, available over the counter. Mark B. McClellan, commissioner of the F. Most over-the-counter medicines sell for far less than prescription drugs because they are older products that lack the protection of patents that ward off competition.