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However, since more evidence is continually emerging and since prices vary, both across countries and with the passage of time, re-evaluation is necessary. Using the Markov chain approach, this paper analyses the relative cost-effectiveness of omeprazole and ranitidine in the intermittent treatment of duodenal ulcer in Great Britain. The importance for the result of inclusion and exclusion of relapses and the length of the time-period studied are also investigated. While both factors are important, the effect of including relapses in the analysis is more important than the effect of extending the time-period. It is found that the treatment alternative with omeprazole is relatively more cost-effective when relapses are excluded compared with when relapses are included.

Two hundred sixty-eight patients with GERD were recruited and randomly assigned to omeprazole sodium, 20 mg once daily, or ranitidine hydrochloride, mg twice daily, for up to 6 months. Medical resource use and cost data were collected. More omeprazole-treated patients reported improved heartburn resolution at 2 weeks Ranitidine and omeprazole were both effective at improving heartburn symptoms; however, omeprazole provided greater resolution of heartburn symptoms at 2 and 4 weeks. Despite omeprazole's higher acquisition cost, there were no significant differences in total or outpatient costs between groups. Frequently asked questions.

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Ranitidine is used to reduce the amount of acid secreted by the stomach in order to reduce ulcer and heartburn pain or to assist in healing of ulcers. It is used to treat stomach and duodenal intestinal ulcers, and prevent them from recurring. Prescription ranitidine is used to treat and prevent stomach ulcers caused by non-steroidal anti-inflammatory drugs NSAIDs ; to prevent bleeding caused by stress ulcers for very ill people; to prevent a second episode of bleeding in the digestive tract caused by bleeding ulcers; and to prevent inhalation of stomach acid during surgery, for people who are considered at risk of this complication. It can also be used to prevent these symptoms when they are associated with eating food or drinking beverages. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.


Select Strength. Ships to U. It works by decreasing the amount of acid made in your stomach.

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All prices are subject to change at any time. The pharmacy usually ships your medication the same day it receives your prescription from the physician, and within 12 to 24 hours of your initial order.

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