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Two hundred sixty-eight patients with GERD were recruited and randomly assigned to omeprazole sodium, 20 mg once daily, or ranitidine hydrochloride, mg twice daily, for up to 6 months. Medical resource use and cost data were collected. More omeprazole-treated patients reported improved heartburn resolution at 2 weeks Ranitidine and omeprazole were both effective at improving heartburn symptoms; however, omeprazole provided greater resolution of heartburn symptoms at 2 and 4 weeks. Despite omeprazole's higher acquisition cost, there were no significant differences in total or outpatient costs between groups. Frequently asked questions.
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Ranitidine is used to reduce the amount of acid secreted by the stomach in order to reduce ulcer and heartburn pain or to assist in healing of ulcers. It is used to treat stomach and duodenal intestinal ulcers, and prevent them from recurring. Prescription ranitidine is used to treat and prevent stomach ulcers caused by non-steroidal anti-inflammatory drugs NSAIDs ; to prevent bleeding caused by stress ulcers for very ill people; to prevent a second episode of bleeding in the digestive tract caused by bleeding ulcers; and to prevent inhalation of stomach acid during surgery, for people who are considered at risk of this complication. It can also be used to prevent these symptoms when they are associated with eating food or drinking beverages. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.