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Oxipurinol is eliminated unchanged in the urine but has a long elimination half-life because it undergoes tubular reabsorption. Reported values for the elimination half-life range from Allopurinol and oxipurinol clearance is greatly reduced in patients with poor renal function resulting in higher plasma levels in chronic therapy.

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In order to prevent bleeding disorders in the offspring, it has also been recommended that vitamin K 1, be given to the mother during the last weeks of pregnancy as well as to the neonate. These reactions may represent a neonatal withdrawal syndrome.

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Date of revision of the text. Each tablet contains baclofen 10 mg. Excipient with known effect: Each tablet contains 40 mg lactose monohydrate For the full list of excipients, see section 6.

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