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Single high-dose fraction therapy to abdomen: 8 mg PO hr before radiation therapy; administer subsequent doses every 8 hr after first dose days after completion of therapy. Daily fractions to abdomen: Administer 8 mg PO hr before radiotherapy; administer subsequent doses every 8 hr after first dose each day radiotherapy is given. Alternatively, mg intermittent short-term IV dosing used in adults; single dose of 4 mg single dose used in pregnancy.

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