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You should not use this medicine if you have glaucoma, overactive thyroid, severe heart problems, uncontrolled high blood pressure, advanced coronary artery disease, extreme agitation, or a history of drug abuse. Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Phendimetrazine is similar to an amphetamine. Phendimetrazine stimulates the central nervous system nerves and brain, which increases your heart rate and blood pressure and decreases your appetite. Do not use phendimetrazine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur.

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The usual dose is 35 mg PO 2 to 3 times per day, given 1 hour before meals. In some cases, Max: Do not exceed 2 tablets 70 mg PO 3 times a day.

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Phendimetrazine is a racemic mixture of the trans configuration, producing both trans isomers of phenmetrazine when metabolized in vivo. Nelson, D. Phendimetrazine is yet another sympathomimetic, CNS-stimulant type of anorexiant.

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