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Adults: 1 x 25mg up to three times daily, increasing stepwise to mg. This should be reached by the end of the first week and maintained until definite improvement has occurred. The subsequent maintenance dose should be individually determined by https://www.lemonaidhealth.com gradually reducing the dosage, usually to about mg daily. In patients in hospital, i. Again the subsequent maintenance dose should be determined individually by reducing the dosage, usually to about mg daily. Elderly: Patients over 60 years may respond to lower doses of imipramine than those recommended above. Treatment should be initiated with 10mg daily, gradually increasing to mg daily. The optimum dose should be reached after about 10 days and then continued until the end of treatment. Children for nocturnal enuresis only : The tablets should be administered just before bedtime. The dose should not exceed 75mg daily.
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